Le numéro 5 de septembre - octobre 2025 est en ligne

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Pharmacodependence

Prévention du mésusage et du risque des surdoses d’opioïdes et diffusion de naloxone : état des lieux des pratiques, besoins et perspectives auprès des pharmaciens d’officine

Prevention of opioid misuse and overdose risk and distribution of naloxone: Current practices, needs and prospects among dispensing pharmacists

Armelle Chan Soc Foh, Salim Mezaache, Franck Turlure, Nathalie Fredon, Stéphane Pichon, Laurent Peillard, Joelle Micallef, Elisabeth Frauger

Pharmacoepidemiology

Validation of in-hospital diagnosis codes in one French hospital and out-hospital algorithm to identify skin ulcers in healthcare databases in France

Clément Jambon-Barbara, N’dah Mathieu Ouattara, Claire Bernardeau, Frédéric Olive, Sophie Blaise, Jean-Luc Cracowski, Charles Khouri

Pharmacovigilance

BRAF and MEK inhibitors rechallenge after an adverse drug reaction in patients with cancer: A pharmacovigilance cohort study

Emilien Ezine, Angélique Da Silva, Safa Idoudi, Céleste Lebbe, Basile Chrétien, Marion Sassier, Joachim Alexandre, Charles Dolladille

COVID-19 infection and risk of adverse drug reactions: Cohort study

Paul-Benoît Fargier, Marlène Damin-Pernik, Manon Launay, Amandine Gagneux-Brunon, Florelle Bellet, Marie-Noëlle Beyens

Lichenoid drug eruption and apalutamide: Analyses from pharmacovigilance databases and disproportionality analysis

Viktoryia Prontskus, Anne Lise Pinault, Lucie-Marie Scailteux, Marie-Noelle Beyens, Audrey Fresse, Nadine Petitpain

Les réactions liées à la perfusion avec les immunoglobulines polyvalentes humaines : analyse de la base nationale de pharmacovigilance française
Infusion-related reactions with human polyclonal immunoglobulins: Analysis from the French National Pharmacovigilance Database

Aurélie Bobet, Justine Bravo, Eyrian Aubin-Beale, Blandine Bertin, François Montastruc, Romain Barus

Association between antidepressant drugs and falls in older adults: A mediation analysis in the World Health Organization's pharmacovigilance database

Elise-Marie Minoc, Cédric Villain, Basile Chrétien, Soumia Benbrika, Marie Heraudeau, Claire Lafont, Clémence Béchade, Thierry Lobbedez, Véronique Lelong-Boulouard, Charles Dolladille

HOPIPRAC : Interface de pharmacovigilance pour la détection de cas d’évènements indésirables dans un entrepôt de données hospitalier
HOPIPRAC: Pharmacovigilance interface for detecting cases of adverse events in a hospital data warehouse

Layal El Aridi, Hélène Jantzem, André Happe, Jean Michel Cauvin, Dominique Carlhant-Kowalski, Greta Gourier

Vaccines and the risk of Guillain-Barré syndrome: A French pharmacovigilance analysis

Marie Gligorov, Bénédicte Lebrun-Vignes, Kamel Masmoudi, Thierry Vial, Helga Junot, Valérie Pourcher, Sophie Demeret, Nicolas Weiss, Kevin Bihan

Intravitreal vascular endothelial growth factor inhibitors and cardiovascular adverse drug reactions: Added value of the data of the French pharmacovigilance spontaneous reporting assessment

Aurélie Bobet, Leila Chebane, Annie-Pierre Jonville-Bera, Marina Babin, Thomas Soeiro, Haleh Bagheri

Therapeutics

Evaluation of efficacy and tolerance of intravesical amphotericin B irrigation for the management of Candiduria

Zahoua Kartit, Maud Hulin, Dominique Hettler, Antoine Huguenin, Morgane Bonnet, Yohan N’Guyen

Letters to Editor

Cutaneous adverse drug reactions induced by anticonvulsants: Proposal for allergological work-up and contraindications

Saskia Ingen-Housz-Oro, Paola Sanchez-Pena, Bénédicte Lebrun-Vignes, Kevin Bihan, Claire Bernier, Brigitte Milpied, Haudrey Assier

Unexpected haloperidol-induced yawning while neuroleptic switch, paradoxical reaction or dopaminergic supersensitivity? A case report

Jacques Hamard, François Montastruc, Dalil Boulefaa, Julie Haybrard, Julien Li

Reintroduction of cotrimoxazole in a Stevens-Johnson case with other antibacterial sulfonamide (sulfadiazine) among suspects

Ilaria Matei, Valérie Beaulieu, Camille Ollivier, Bénédicte Lebrun-Vignes, Kamar Bel Hareth, Saskia Ingen-Housz-Oro, Haudrey Assier

Preventing shingles starts with vaccinating against chickenpox

Michaël Rochoy

Rapid desensitization to insulin in a patient with diabetic ketoacidosis and insulin allergy

Emna Chtourou, Fatma Charfi, Imen Chabchoub, Hanen Ghozzi, Ahmed Hakim, Kammoun Thouraya, Khaled Zeghal, Lobna Ben Mahmoud

Subcutaneous rituximab in indolent primary cutaneous B cell lymphoma: A case series of 5 patients with the evaluation of the medico economic impact

Carla Fassanaro, Laurent Mortier, Olivier Carpentier, Inès Arib, Benoit Dervaux, Sarah Faiz

Methylphenidate-associated eosinophilia in a child: A case report

Aurélie Bobet, Marion Broquere, Philippe Pauly, Thiébaut-Noël Willig, Haleh Bagheri

Pharmacology and artificial intelligence

Artificial intelligence for precision medicine

Marie-Elise Martel, Adan José-Garcia, Celine Vens, Maarten De Vos, Vincent Sobanski

Artificial intelligence in personalized prescription: A narrative review of promise, peril, and practicality

Guillaume L. Martin, Louis Létinier

Suivi thérapeutique pharmacologique

Livre blanc de la pharmacologie biologique
Biological pharmacology: A white paper

Florian Lemaitre, Caroline Monchaud, Matthieu Grégoire, Romain Guilhaumou, Françoise Goirand, groupe de travail « Suivi thérapeutique pharmacologique et personnalisation des traitements de la Société française de pharmacologie et de thérapeutique »

Pharmacology and artificial intelligence

Digital pharmacological twins: Bridging multi-scale modelling and artificial intelligence for precision medicine: The DIGPHAT consortium

Jean-Baptiste Woillard, Sébastien Benzekry, Julie Josse, Mélanie White-Koning, Etienne Chatelut, Emmanuelle Comets, Florian Lemaitre, Bénédicte Franck, Matthieu Gregoire, Françoise Stanke-Labesque, Sarah Zohar, Moreno Ursino, Christophe Battail, on behalf of the DIGPHAT consortium

A new chapter in pharmacology: Artificial intelligence's expanding role in pharmacokinetics, pharmacodynamics, and pharmacovigilance

Alexandre O. Gérard, Romain Lombardi, Diane Merino, Charles Bouveyron, Jean Dellamonica, Milou-Daniel Drici, Thibaud Lavrut, Alexandre Destere

Pharmacovigilance

Isolated depressive disorders and suicidality with finasteride use for androgenetic alopecia: A call for enhanced vigilance

Hélène Géniaux, Marie-Laure Laroche

Letter to editor

Fluoxetine-induced lower limb ecchymosis in an adolescent: A case report and literature review

Thomas Darque, Clément Pruvot, Paul Nadin, Paola Sanchez-Pena, Myrtille Hamm, Juliette Miquel